sodium lauryl cocrystal

A commonly used pharmaceutical surfactant sodium lauryl sulfate SLS has been reported to reduce the dissolution rate of drugs due to the formation of a less soluble drug lauryl sulfate salt

Cocrystal solubility pH and drug solubilization capacity of sodium dodecyl sulfate Mass action model for data analysis and simulation to improve design of experiments

Cocrystal solubility stability and eutectic points were investigated as a function of pH and sodium lauryl sulfate concentration for a series of carbamazepine cocrystals in water The cocrystals represented two stoichiometries 1 1 and 2 1 and four coformers salicylic acid saccharin aminobenzoic acid and succinic acid with various

The thermodynamic solubility of cocrystal was determined in phosphate buffer solution pH 6 8 and in the presence of different concentrations of sodium lauryl sulfate SLS and polyvinylpyrrolidone PVP followed by investigating their effects on solution stability of cocrystal

12 ensp 0183 ensp Engineering cocrystal solubility stability and pHmax by micellar solubilization Journal of Pharmaceutical Sciences 2011 100 12 5234 DOI 10 1002 jps 22725 Kristyn Greco Robin Bogner Solution Mediated Phase Transformation of Haloperidol Mesylate in the Presence of Sodium Lauryl

Predictions are in excellent agreement with the behavior of several carbamazepine cocrystals in aqueous solutions of sodium lauryl sulfate Increasing the magnitude of micellar solubilization for one of the cocrystal components is found to confer greater thermodynamic stability to the cocrystal and expand its

US8871793B2 US13 518 13518177A US8871793B2 US 8871793 B93 B2 US 8871793B2 US 201013518177 A US201013518177 A US 201013518177A US 8871793 B93 B2 US 8871793B2 Authority US United States Prior art keywords metaxalone cocrystal 2θ acid cocrystal powder Prior art date 23 Legal status The legal status is an assumption and is not a legal

The influence of the surfactants of sodium lauryl sulfate SLS and Tween 80 on carbamazepine–nicotinamide CBZ–NIC cocrystal solubility and dissolution behaviour has been studied in this work The solubility of the CBZ–NIC cocrystal was determined by measuring the eutectic concentrations of the drug and the coformer Evolution of the intrinsic dissolution rate IDR of the

Experimental results with indomethacin saccharin cocrystal IND SAC and surfactants sodium lauryl sulfate Brij and Myrj demonstrate the log linear relationship characteristic of SA SP

This review discusses the disposition of the anionic surfactant sodium dodecyl sulfate SDS i e sodium lauryl sulfate to solubilize sparingly soluble drugs above the surfactant critical micelle concentration CMC as quantitated by the solubilization capacity k A compilation of 101 published SDS k values of mostly poorly soluble drug molecules was used to develop a prediction model

The invention relates to a novel betaine cocrystal of lZ 2E methyl phenylpropenylidene oxo thioxo thiazolidineacetic acid The preparation and characterization of the novel betaine cocrystal according to various embodiments of the invention is described The invention also relates to pharmaceutical compositions containing the novel betaine cocrystal and the therapeutic use of

The influence of the surfactants of sodium lauryl sulfate SLS and Tween 80 on carbamazepine nicotinamide CBZ NIC cocrystal solubility and dissolution behaviour has been studied in this work

16 ensp 0183 ensp 1 , Crystal Pharmatech Email sales crystalpharmatech com 69561921

6 ensp 0183 ensp The solubility CSC and pH max of carbamazepine cocrystals in micellar solutions of sodium lauryl sulfate predicted by the models are in very good agreement with experimental measurements The findings from this work demonstrate that cocrystal CSC and pH max can be tailored from the selection of coformer and solubilizing additives such as

Solution Mediated Phase Transformation of Haloperidol Mesylate in the Presence of Sodium Lauryl Sulfate

The phase diagrams for carbamazepine CBZ and nicotinamide NCT in ethanol and ethanol ethyl acetate mixture were constructed at 298 15 K and 313 15 K under atmospheric pressure using the static method The solubility of the 1 1 cocrystal is correlated as a function of the cocrystal former nicotinamide concentration by a mathematical model based on solubility product theory and the

11 ensp 0183 ensp The influence of the surfactants of sodium lauryl sulfate SLS and Tween 80 on carbamazepine nicotinamide CBZ NIC cocrystal solubility and dissolution behaviour has been studied in this work The solubility of the CBZ NIC cocrystal was determined by measuring the eutectic concentrations of the drug and the coformer

The influence of the surfactants of sodium lauryl sulfate SLS and Tween 80 on carbamazepine–nicotinamide CBZ–NIC cocrystal solubility and dissolution behaviour has been studied in this work The solubility of the CBZ–NIC cocrystal was determined by measuring the eutectic concentrations of the drug and the coformer

Citation Li M Qiao N and Wang K 2013 Influence of Sodium Lauryl Sulfate and Tween 80 on Carbamazepine–Nicotinamide Cocrystal Solubility and Dissolution Behaviour Pharmaceutics 5

Engineering Cocrystal Solubility Stability and pH max by Micellar Solubilization max of carbamazepine cocrystals in micellar solutions of sodium lauryl sulfate predicted by the models are

This review discusses the disposition of the anionic surfactant sodium dodecyl sulfate SDS i e sodium lauryl sulfate to solubilize sparingly soluble drugs above the surfactant critical micelle concentration CMC as quantitated by the solubilization capacity k

Cocrystal solubility pH and drug solubilization capacity of sodium dodecyl sulfate – mass action model for data analysis and simulation to improve design of experiments Alex Avdeef in ADME Research 1732 First Avenue 102 New York NY 10128 USA

BibTeX MISC Li13articleinfluence author Mingzhong Li and Ning Qiao and Ke Wang title Article Influence of Sodium Lauryl Sulfate and Tween 80 on Carbamazepine–Nicotinamide Cocrystal Solubility and Dissolution Behaviour year 2013

25 ensp 0183 ensp Experimental results with indomethacin saccharin cocrystal and surfactants sodium lauryl sulfate Brij and Myrj demonstrate the log linear relationship characteristic of SA–SP diagrams and the dependence of σmax and dissolution area under the curve AUC on SA with characteristic maxima at a threshold supersaturation where drug nucleation